Preparation and Characterization of New Compound by Electrochemical Oxidation of Methyl Catechol in the Presence of 2-Thiouracil

Document Type : Research Paper

Abstract

The electrochemical oxidation of methyl catechol in the presence of 2-thiouracil (as a nucleophile) has been
performed in aqueous solutions using cyclic voltammetry and controlled-potential coulometric techniques.
The electrochemical behavior of methyl catechol in the presence of 2-thiouracil was investigated. The
electrochemical synthesis of this compound has been successfully performed in an undivided cell in a good
yield and purity and was characterized by IR, 1H and 13C NMR. According to the results obtained from
1H NMR, 13C NMR it is concluded that methyl o-quinones are attached in all probably only in the its C4
position to 2-thiouracil from S position leading to the formation of 2-(4,5-dihydroxy-2-methylphenylthio)
pyrimidin-4(3H)-one (DMPTP).

Keywords

• Methyl catechol
• 2-Thiouracil
• Electro-organic synthesis

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